STUDIES ON PHYTOCHEMICAL EVALUATION OF Tamarindus indica EXTRACTS AS ANTI-SNAKE VENOM AGENTS SAILAKSHMI.T*, C.S.V. RAMACHANDRA RAO, RAVI3

نویسنده

  • C. S. V. RAMACHANDRA RAO
چکیده

Many medicinal plants have been recommended for the treatment of snakebites. Aqueous and alcoholic extracts of dried seed powder of Tamarindus indica were tested for their antioxidant and inhibitory activity of toxic enzymes like PLA2 and proteinases of Naja naja venom. Compared with alcoholic extracts the methanolic extract, displayed a significant inhibitory effect on the tested enzyme activities of venom. The present finding suggests that the methanolic extracts of T. Indica seed possess compounds, which inhibit the activity of Phospholipase A2 and Proteinases of cobra venom.It may be used as an alternative treatment to serum therapy and as a rich source of potential inhibitors of toxins involved in several pathological conditions of humans and animal diseases.

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تاریخ انتشار 2012